Duane Keiser studied painting under Raymond Berry at Randolph-Macon College in Ashland, Virginia andLennart Anderson at Brooklyn College in NYC. His "A Painting a Day" blog has been written about in numerous publications, including USA Today, The New York Times and The Huffington Post. Using a makeshift easel made from a cigar box, he makes a postcard-sized painting each day and posts them to his blog where collectors can bid on them via eBay. The project is ongoing and can be seen here. He is also known for his "painted animations." A modern take on the still life, these videos combine traditional painting, animation, and time-lapse.

He has exhibited at Fischbach Gallery, Allan Stone Gallery and, most recently, the New York Academy of Art. His work resides in several corporate collections and hundreds of private collections worldwide, including the Gregory Peterson Collection.